Motion Sickness, Stress and the Endocannabinoid System

Motion Sickness, Stress and the Endocannabinoid System

BACKGROUND A substantial number of individuals are at risk for the development of motion sickness induced nausea and vomiting (N&V) during road, air or sea travel. Motion sickness can be extremely stressful but the neurobiologic mechanisms leading to motion sickness are not clear. The endocannabinoid system (ECS) represents an important neuromodulator of stress and N&V. Inhibitory effects of th...

The Endocannabinoid System and Stress

Introduction One of the environmental factors that precipitates and exacerbates mental illnesses, including depression, anxiety disorders, and substance abuse, is repeated life stress. For example, homotypic stressors that occur on a daily basis, such as poverty or medical problems, are associated with increased depressive symptoms [1]. Not everyone exposed to stress has pathological consequenc...

Endocannabinoid-mediated modulation of stress responses: physiological and pathophysiological significance Short title: Endocannabinoid system and stress

Unusual presentation of motion sickness: Case report

Introduction: Motion sickness is a normal response to real. Perceived or anticipated movement. Although the prognosis is excellent it may be incapacitating for people with an occupation that requires constant movement, such as a flight attendant, pilot, astronaut, or ship crew members. The symptoms progresses from initial dizziness to vomiting. Fortunaterly most symptoms disappear once the stim...

Motion sickness

The term motion sickness was originally introduced to provide a nosological classification for disorders elicited by exposure to unusual patterns of motion, such as sea sickness, train sickness, and swing sickness. The term came to subsume air sickness as well, and in recent years, simulator sickness, space sickness, and cybersickness (virtual environment sickness). It is now recognized that bo...